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4.13: Ribozimas

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    53546
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    Figura 4.12.1: Imagen que muestra la diversidad de estructuras de ribozima. De izquierda a derecha: leadzyme, ribozima martillo, ribozima twister. Imagen utilizada con permiso de Wikipedia (CC-BY-SA-4.0 y crédito: Lucasharr).

    Las ribozimas, sin embargo, no son raridades de la naturaleza. Los ribosomas productores de proteínas de las células son esencialmente ribozimas gigantes. El ARNr 23S del ribosoma procariota y el ARNr 28S del ribosoma eucariota catalizan la formación de enlaces peptídicos. Las ribozimas también son importantes en nuestra comprensión de la evolución de la vida en la Tierra. Se ha demostrado que son capaces a través de la selección para evolucionar la autorreplicación. De hecho, las ribozimas realmente responden a un dilema de pollo/huevo -que vino primero, enzimas que hacen el trabajo de la célula o ácidos nucleicos que portan la información requerida para producir las enzimas. Como portadores de información genética y catalizadores, las ribozimas son probablemente tanto el pollo como el huevo en el origen de la vida.

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    This page titled 4.13: Ribozimas is shared under a CC BY-NC-SA license and was authored, remixed, and/or curated by Kevin Ahern & Indira Rajagopal.