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    • https://espanol.libretexts.org/Quimica/Libro%3A_Qu%C3%ADmica_Org%C3%A1nica_con_%C3%A9nfasis_Biol%C3%B3gico_(Soderberg)/11%3A_Reacciones_de_adicion_nucleofilica_de_carbonilo
      In carboxylic acid derivatives, the heteroatom bonded to the carbonyl carbon on one side is a potential leaving group, whereas in aldehydes and ketones the hydrogen and/or carbon is definitely not a g...In carboxylic acid derivatives, the heteroatom bonded to the carbonyl carbon on one side is a potential leaving group, whereas in aldehydes and ketones the hydrogen and/or carbon is definitely not a good leaving group, so the two categories of compounds react in fundamentally different ways.

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