In the first step of virtually all PLP-dependant reactions, the aldehyde group of the coenzyme forms an imine (Schiff base) linkage with a lysine side chain on the enzyme. (In order to help you to foc...In the first step of virtually all PLP-dependant reactions, the aldehyde group of the coenzyme forms an imine (Schiff base) linkage with a lysine side chain on the enzyme. (In order to help you to focus on the chemistry happening with the amino acid substrates, the PLP molecule in subsequent figures is colored green - it will be very helpful to refer to color figures).
